As much fun as it would be to burn a few points downvoting spammers like Los Angeles Criminal Lawyer, Atlanta Data Center, and Refrigerators on the Bulletin board software with voting capability for each post thread, seems like it'd be just as productive to have the option to flag a user profile as obvious spam (whether or not the profile is associated with new posts).
Running a few popular vBulletin forums, I've seen spammers register just to have a profile with a link back to their site in it (many never bothered posting) so it would only make sense to add a Flag Profile option.
Edit
Closed per re-post at StackOverflow Meta (apparently the accepted solution is to contact a mod or post on meta).